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The NLRP3 inflammasome is a complex consists of a sensor (NLRP3 protein), an adaptor (apoptosis-associated speck-like protein, ASC), and an effector (caspase-1)
PubMed Teichman, S.L., Neale, A., Lawrence, B., Gagnon, C., Castaigne, J.P., & Frohman, L.A

They also noticed that in the absence of HGF, TGF- (an EGFR ligand) activates c-MET when EGFR is blocked [101]

These usually resolve within hours to a few days
