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Magnesium blocks N -methyl-d-aspartate (NMDA) receptors in a voltage-dependent manner, preventing the development of central sensitization

To add to that, one may experience increased heart rate and blood pressure, serious cardiovascular reactions, psychiatric adverse reactions such as psychotic or manic symptoms, and serotonin syndrome

[DOI] [PubMed] [Google Scholar] 13.Greig C, Finch KM, Jones DA, Cooper M, Sargeant AJ, Forte CA