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Proceedings of the European Society for the Study of Drug Toxicity 10, 57

10.1038/nri1312 [DOI] [PubMed] [Google Scholar] Lapouge K., Smith S., Walker P., Gamblin S., Smerdon S., Rittinger K

It is an essential low-molecular-weight thiol, which fulfills a broad range of functions including as an electron-donating co-factor in biochemical reactions (Noctor and Foyer, 1998

Furthermore, oxidative stress can trigger additional apoptotic pathways, including the JNK and p53 signaling cascades, which can further exacerbate the death of hair cells [41,42]

doi: 10.1016/j.fct.2010.10.002
