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Description
Overdoing it can occasionally lead to side effects like nerve irritation (with too much B6), skin flushing (from high-dose B3), or digestive upset

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After 3 months, take a 2-month break before repeating

Some side effects like alteration of the CNS, peripheral vascular tone, and cardiac function might occur

The Mayo Clinic notes that people with pernicious anemia, gastrointestinal surgery, or certain malabsorption conditions often cannot absorb oral B12 effectively, making injections the preferred route for correcting clinically diagnosed deficiency