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A positive feedback loop between Akt and mTORC2 via SIN1 phosphorylation

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Ziegler, A

Clinical and preclinical studies have revealed that AKI is a complex systemic disease with effects on virtually every organ 2 , including the lung 3,4 , heart 5,6 , liver 7,8 , brain 9 , and intestine 10

For example, in their comprehensive review, Wang et al 133 concisely outline the design methodologies employed in the development of self-assembled peptide nano-drug delivery systems