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W., Grassian, A

Increased levels of programmed cell death 5 (PDCD5) subsequently ameliorated progressive fibrosis and cardiac dysfunction by inhibiting histone deacetylase 3 (HDAC3), suggesting that PDCD5 serves as an endogenous negative feedback regulator in progressive cardiac fibrosis [109]
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LINGO-1 negatively regulates myelination by oligodendrocytes

10.1073/pnas.95.12.7157 [DOI] [PMC free article] [PubMed] [Google Scholar] Zhang L., Loh H

The link is (surprise!) mitochondria
