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2005 Aug;15(4):386-400

Its FDA-cleared for treating insomnia and is believed to work by improving brain function

doi: 10.1080/10717544.2017.1377316

188 Ketamine is also known to cause more serious side effects, such as hallucinations, impaired consciousness, cognitive dysfunction, high blood pressure, cystitis (bladder inflammation), and liver and gallbladder dysfunction, and should be used with caution

oxidation phosphorylation (from the leakage of electrons in the electron transport chain) (Murphy, 2009), oxidation catalysed by metals and reaction of NADPH oxidase as reported in the respiratory burst of phagocytes (Robinson, 2008)