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Oxidative and reductive processes in biological systems Oxidation of proteins in cells can be (i) part of a normal enzymatic mechanism, (ii) caused by reactive oxygen species (ROS) elicited as a side product through leakage of electrons from the electron transport chain during normal metabolism, (iii) a result of ROS generated from toxins or damaging agents, or (iv) evoked following the regulated generation of cellular oxidants for signaling purposes (Fig

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