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Conclusion MDSCs are pivotal mediators of immune evasion in cancer, playing a dual role in both immunosuppressive and non-immunosuppressive tumor-promoting activities, such as supporting cancer stem cell survival, inducing angiogenesis, driving the epithelialmesenchymal transition, and contributing to the formation of pre-metastatic niches
There is no upper limit (UL) because toxicity due to high dosage is unlikely
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HuKChenXChenWZhangLLiJYeJet al
