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J Ethnopharmacol 129(2):142166 Jainu M, Devi CS (2006) Antiulcerogenic and ulcer healing effects of Solanum nigrum (L.) on experimental ulcer models: possible mechanism for the inhibition of acid formation

Alternatively, peptide bond surrogates can have protease inhibitor activity at the substrate cleavage site, and therefore offer a fundamental strategy for understanding protease enzyme activity, especially if isosteres can imitate the transition state of bond degradation (hydrolysis)
Revista Colombiana De Reumatologa (English Edition)

10.1158/0008-5472.can-20-0471 150 WadhwaS.MumperR

Although overexpression of isoforms such as ALOX5, ALOX12, and ALOX15 can sensitize cells to ferroptosis (Yang et al., 2022), none of the isoforms has yet been proven to play a decisive role in ferroptosis