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At 12mg weekly, trials show 24.2% weight loss at 48 weeks and up to 28.7% at 68 weeks in Phase 3

[DOI] [PMC free article] [PubMed] [Google Scholar] Leung A.K., Tam Y.Y., Chen S., Hafez I.M., Cullis P.R

MRP2, Multi-drug Resistance-associated Protein 2

Lia Z, Dua Y, Zhang Z, Pang D (2003) Preparation and characterization of CdS quantum dots chitosan biocomposite

Studies have shown significantly reduced GPX3 mRNA levels in chondrocytes from KBD patients, where elevated methylation of CpGs in the GPX3 gene suppresses its transcription, reducing antioxidant function and promoting chondrocyte apoptosis, thus accelerating KBD progression [205,206]