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Berens, Cancer and Cell Biology Division, The Translational Genomics Research Institute, 445 N 5th Street, Phoenix, Arizona 85004, USA Stuart L

A: In some clinical studies, oral glutathione at 250500 mg/day showed modest reduction in melanin and improved skin radiance in sun-exposed areas

One of the drugs, which can cross BBB and act directly on cells of CNS, causing decreased myelination, is 5-FU (Han et al., 2008)

Shendure J, Mitra RD, Varma C, Church GM

The neuroprotective effects of edaravone are shown in the meta-analysis of randomized controlled trials and prospective cohorts on edaravone [39]
