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Furthermore, the study revealed that in an acute p21 overexpression model, HGF + EGF mRNA-LNP therapy elevated the survival rate of primary cells, thereby ameliorating liver pathology

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Antioxid Redox Signal 14: 543558, 2011 [DOI] [PMC free article] [PubMed] [Google Scholar] 31.Gupte RS, Floyd BC, Kozicky M, George S, Ungvari ZI, Neito V, Wolin MS, Gupte SA

Other data supporting ROS participation in this process are that N-acetylcysteine restores total myocardial glutathione, lowers oxidative stress, and reduces myocyte hypertrophy and fibrosis in aortic stenosis rats [153]