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Nature 437 , 497504 (2005)

Analysis of pooled data To increase the sample size and BW range, five independent experiments totalling 145 rats were pooled into vehicle (V, n = 38), drug (CS + C + S, n = 57) and calorie restriction (WM + PF, n = 50) groups (Extended Data Table 1)

Individual response and healthcare provider recommendations determine the precise timing between injections, allowing for personalized treatment protocols that optimize results while maintaining safety

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Researchers use IGF-1 LR3 to study cellular growth, tissue regeneration, and metabolic signaling in controlled laboratory and preclinical models
