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The participants were divided into the following experimental groups or a placebo group: 1 mg of retatrutide (subcutaneously) 4 mg of retatrutide (subcutaneously), starting at an initial dose of 2 mg 4 mg of retatrutide (subcutaneously), starting at an initial dose of 4 mg 8 mg of retatrutide (subcutaneously), starting at an initial dose of 2 mg 8 mg of retatrutide (subcutaneously), starting at an initial dose of 4 mg 12 mg of retatrutide (subcutaneously), starting at an initial dose of 2 mg Here are the detailed results of the trial at 24 weeks and 48 weeks: Phase II clinical trial projects promising results of retatrutide in weight management

(138) demonstrated that administration of a single dose short-acting GLP-1RA exenatide increased GH levels, whereas administration of long-acting GLP-1RA liraglutide daily for 21 days elicited increased GH levels with no changes in IGF-I levels in healthy subjects

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It was approved for use in 1985