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Statistical Analysis Statistical analysis was performed by parametric one-way analysis of variance (ANOVA), with post-hoc NewmanKeuls test and non-parametric KruskalWallis test and subsequently the MannWhitney U test to compare groups

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Apitolisib, Bimiralisib, Paxalisib, Samotolisib, and Voxtalisib showed moderate intestinal absorption, while Apitolisib, Samotolisib, and Voxtalisib exhibited limited hepatic metabolism, suggesting potential for enhanced systemic exposure

The ascorbate free radical is reduced back to ascorbate within cells by enzymes NADH- and NADPH dependent reductases that have a high affinity for the low concentrations of the radical generated [11]

Hermansen, K., Bengtsen, M., Kjaer, M., Vestergaard, P
