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Genetics 118 , 7586 (1988)

Dietary heme alters microbiota and mucosa of mouse colon without functional changes in host-microbe cross-talk

Taken together with prior studies, these observations suggest a model (Figure 8) whereby many of the metabolic effects of mTORC1 inhibition are likely mediated through activation of C/EBP-, and that both mTOR and C/EBP- are druggable targets to induce positive effects in the context of diet-induced obesity

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One paper [26] reviewing diabetic neuropathy included two RCTs [10,28] and concluded that ALC could relief neuropathic pain, while another paper reviewing HIV-associated neuropathy included one RCT [11] and suggested no superiority of ALC to placebo