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Acknowledgements The present study was funded by the National Research Foundation of Korea through the Basic Science Research Program (NRF-2017M3A9B4061890, NRF-2017R1D1A1B03035059, NRF-2017M3A9D8062960, and NRF-2018R1A2B3008541)

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Without adequate circulation, the injured tissue cannot receive the oxygen and nutrients necessary for repair, nor can it efficiently remove metabolic waste products
