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In the TME histone lactylation upregulates YTHDF2 which promotes tumorigenesis by degrading PER1/TP53 mRNA (119)

Notably, Ero1 knockdown has been found to mitigate HHcy-induced ER oxidative stress and inflammation

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Diagnosing MS involves a combination of tests, including a physical exam, MRI imaging, and possibly a spinal tap to analyze cerebrospinal fluid

G-6-P, glucose-6-phosphate
