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6.2.2 The impact on ulcerative colitis In a dextran sulfate sodium-induced ulcerative colitis mouse model, silybin alleviates colitis by remodeling the gut microbiome and promoting the production of the key metabolite (R)-2,3-dihydroxyisovaleric acid by beneficial bacteria

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Other forms of programmed cell death include ferroptosis [44], necroptosis [72], and pyroptosis [73], depending on exposure intensity and cellular context