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Researchers studying metabolic dysfunction in adipose tissue have identified NNMT as one of the most consistently upregulated enzymes in obese white fat, making it a high-confidence therapeutic target for metabolic intervention
doi: 10.3390/nu14112253
Cross-reference against the charts in this article
Vitamin B12 plays an important role in cell function, DNA synthesis, metabolising amino and fatty acids, and the formation of red blood cells
While speculative, early research suggests microbiome composition influences metabolic health outcomes independently and may be modifiable to improve treatment response
