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Hallmarks of sex bias in immuno-oncology: mechanisms and therapeutic implications

The CTCAE v5.0 includes a series of signs, symptoms, and laboratory alterations attributed to antineoplastic therapies, in which a total of 47 dermatological AEs are included and graduated according to their severity via a 5-point scale ranging from Grade 1 (mild, asymptomatic, or few symptoms requiring only clinical observation without intervention or preventive treatment if available) to Grade 5 (death from AE) (Table 8)