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Since dermal periostin in PN shows no significant correlation with other pruritogenic mediators in the dermis (including IL-31, IL-31R, and OSMR), it might be an independent contributor to pruritus in PN (64)

Mechanistically, CS promoted -cell proliferation and protected -cells against apoptosis under stressful conditions, which in turn preserved -cell mass

IL-13 also promotes the differentiation of fibroblasts into myofibroblasts and increases TGF expression 84

Pratap Sandhu, CEO of The Precision Peptide Company, commented: "This is the product that brings peptides into the mainstream

doi: 10.1007/s10522-006-9002-5