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Thats why this article aims to dissect the evidence with precision, walk through its mechanistic layers, and separate signals from speculation

Expression of type I insulin-like growth factor receptors on human peripheral blood mononuclear cells

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The high VEGF levels, associated with better responses to antipsychotics, might be predictive of the use of first-generation antipsychotic drugs, whereas low VEGF levels, expression of resistance to therapy, might be predictive of the use of second-generation antipsychotic drugs) [294]