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Evidence derived from human observational studies, autopsy findings, and experimental models suggests that sustained androgen receptor overstimulation may induce structural, functional, and metabolic alterations that compromise cardiovascular homeostasis (68, 69)

These mutations were shown to induce a loss-of-function and led to an increase in trimethyllysine in the plasma of patients[44]

PAG is an end product of phenylalanine metabolism dependent on gut microbiota

Coenzyme Q10: From bench to clinic in aging diseases, a translational review

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