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DHFR and leukemia The expression level of DHFR in leukemia cell lines (Jurkat, Nalm-6, Reh, K562, and Molt-4) was significantly higher compared to normal hematopoietic cells

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As mentioned above, selenocysteine is an important amino acid of the GPX4 active sites
The reactions with some compounds, such as benzyl and phenethyl isothiocyanates and alkyl dihalides, can be reversible, increasing their toxicity [210]

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