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doi: 10.1007/s00394-013-0561-3
Preclinical animal studies further validate its neuroprotective potential: phillyrin A improves learning and memory in senescence-accelerated mice, activates the Nrf2 signaling pathway in APP/PS1 mice, upregulates antioxidant proteins (NQO1, GPX4), and normalizes cerebral iron content through modulation of TFRC, DMT1, FTH, and FTL gene expression (234)
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Inhibition of SARS pseudovirus cell entry by lactoferrin binding to heparan sulfate proteoglycans
