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Simmonds MC, Brown JV, Heirs MK, Higgins JP, Mannion RJ, Rodgers MA, et al

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How the Liver Handles Tylenol The liver metabolizes almost all of it (see diagram above): 90% : Processed safely through glucuronidation and sulfation 2%: Eliminated through the kidneys (urine) 510% : Processed by the enzyme CYP2E1 creates a toxic byproduct called NAPQI (N-acetyl-p-benzoquinone imine)

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