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The implications of NNMT inhibition extend far beyond simple cofactor availability, influencing fundamental cellular processes including mitochondrial biogenesis, oxidative stress management, and epigenetic regulation

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Changes in the cellular levels of high-energy compounds (i.e., ATP and its catabolites, NAD and GTP), GSH, GSSG, and malondialdehyde (MDA) were simultaneously analyzed by ion-pairing HPLC

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