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Notably, HIF stabilization agents like roxadustat show dual benefits, enhancing endothelial cells' resilience while suppressing pericyte hyperactivation in preclinical models [126]

[DOI] [PMC free article] [PubMed] [Google Scholar] 91.Regulation (EU) No 1169/2011 of the European Parliament and of the Council of 25 October 2011 on the Provision of Food Information to Consumers, Amending Regulations (EC) No 1924/2006 and (EC) No 1925/2006 of the European Parliament and of the Council, and Repealing Commission Directive 87/250/EEC, Council Directive 90/496/EEC, Commission Directive 1999/10/EC, Directive 2000/13/EC of the European Parliament and of the Council, Commission Directives 2002/67/EC and 2008/5/EC and Commission Regulation (EC) No 608/2004 Text with EEA Relevance

B vitamins supplementation can improve cognitive functions and may relate to the enhancement of transketolase activity in a rat model of cognitive impairment associated with high-fat diets