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The melanocytes may populate the epidermis as nests only along the dermal-epidermal junction (junctional nevus) ( Fig

This case implies that the melanosis pigment-laden macrophages formed in the lamina propria of the colon pass to the regional lymph nodes and may explain the observation of similar pigment-laden macrophages in other sites

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Melanocytic activation is characterized by hyperpigmentation of the matrix epithelium, secondary to activation of the suprabasal layer melanocytes in the proximal matrix and basal layer melanocytes in the distal matrix, without an increase in the number of melanocytes [1] (Fig