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A Disorder of Cortical GABAergic Innervation in Alzheimer's Disease. Neuroscience Letters 73: 192196

R.DevineA.ZhuK.LimW

In summary, Ghrelin, Neuritin, GAA, and Artemisinin may mitigate cerebral neuronal injury and cognitive dysfunction by modulating neuronal ferroptosis, lipid peroxidation, the antioxidant system, oxidative stress, mitochondrial dysfunction, and neuroinflammation

The study found the peptide well-tolerated with minimal toxicity risk, though adverse events were described as mild to moderate

Another mechanism linking oxidative stress to altered gene expression associated with inflammation is the through inactivation of proteasomes