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Omega-3 is important to normal immune system response and can also suppress the production of inflammatory substances

The impact of the microbiota on the DNA methylome in colonic or small intestinal epithelial cells is most probably restricted to specific gene sets and does not affect the DNA methylation pattern on a global scale (157, 163)

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in which 56 patients with acute ischaemic stroke underwent recanalisation therapy (30 with intravenous thrombolysis, 15 with mechanical thrombectomy, and 11 with both methods combined) revealed that the plasma levels of isovalerate, one of the SCFAs, were inversely correlated with stroke severity as measured by the National Institutes of Health Stroke Scale (NIHSS) both on admission and at discharge, while TMAO levels were not associated with stroke severity (as measured by the NIHSS) or functional outcome (as measured by the Modified Rankin ScalemRS) [57]

CCAAT/enhancer-binding protein homologous protein (CHOP) deficiency attenuates heatstroke-induced intestinal injury