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2021;398(1) doi: 10.1016/j.yexcr.2020.112362
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That can compress startup timelines relative to an IND or an EU CTA, provided the HREC has the expertise to take on the product
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Moreover, the copper chelator D-penicillamine, which is helpful in Wilson disease, does not have therapeutic impact in reversing cholestasis induced liver injury (60)
