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Likewise, it led to a marked downregulation of COX-2 and iNOS, which led to the suppression of NF-B

A common pattern involves using higher doses (2mg daily) during the first cycle, then transitioning to maintenance doses (1mg 2-3x weekly) for subsequent cycles

MASLD is recognized as the most common liver disease globally, affecting approximately 30% of the population, with its prevalence increasing from 22% to 37% over the past two decades [2]

Environ Pollut 240:227234

It functions by interacting with the genome of pathogens through selective binding with the DNAs minor groove, just like curcumin, and disrupts regular activities of the pathogenic topo-isomerases (Neidle, 2001