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Clinical data on several biomarkers such as heart rate, blood pressure and breathing, gathered during testing showed that IQOS is not detectably different from a conventional cigarette, according to Glantz

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Other investigators who believe that tobacco smoke, particularly cigaret smoke, is partly responsible for the increased incidence of cancer of the bronchi and the lungs are Perret, Joannovic, Kanngiesser, Berblinger, Fahr, Hochstetter, Ferenczy and Matolcsy and Schonherr

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Prenatal tobacco exposure has been associated with negative behavioral and cognitive outcomes in childhood, adolescence, and young adulthood