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There is compelling evidence of an association between TB and smoking habits, in terms of increased risk of poorer outcome and defaulting on antituberculosis treatment (Miller et al., 1982

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This population group is considered as most sensitive to compare differences in PK and safety parameters as no immunosuppressive medications or underlying disease conditions affect the study outcome as per the ICH-GCP guidelines

A: No, the battery has protection against overcharge and over-discharge