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Therefore, in addition to exposure doses that tend to mimic the real-life conditions of e-cigarette use, unrealistically high doses can also be used without being fundamentally objectionable if the ultimate goal is to demonstrate dose-dependent effects that are very helpful in terms of elucidating mechanistic aspects of the toxicological process, even though such doses would neither be applicable nor would make sense in in vivo studies, and thus require special attention when interpreting the results

The study was deemed exempt by the Institutional Review Board since there are no human subjects involved in the study

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a half-pack smoker, about 1015 mg

With wildfires becoming more frequent and severe due to climate change and human activity, concerns are growing about the health risks of breathing in wildfire smoke