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These include liver and colorectal cancer, diabetes mellitus, ectopic pregnancy, erectile dysfunction, age-related macular degeneration, orofacial clefts in newborns (as a result of maternal smoking), rheumatoid arthritis, and health problems such as inflammation and impaired immune functioning

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The smallest of the four schools on Tobacco Road, Wake Forest grew up in the sleepy farming hamlet of the same name, located just north of Raleigh's city limits and equally close to the eastern edge of Durham

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