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Quitting Smoking: Nicotine withdrawal from cigarette smoking causes irritability, cravings, anxiety, and trouble concentrating

Ozone (O3) is highly reactive

[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Forecasting the effects of smoking prevalence scenarios on years of life lost and life expectancy from 2022 to 2050: a systematic analysis for the Global Burden of Disease Study 2021

And the other manufacturers took notice: RJ Reynolds, American Tobacco, Brown and Williamson, Liggett, and Lorillard all worked hard to figure out Marlboros secret and by the 1970s and 1980s had developed their own versions of ammonia technology, which all but Liggett implemented commercially