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Archived from the original on 19 November 2017

The Spanish had introduced tobacco in Europe in the sixteenth century and the demand for the product started to grow quickly The massive factory, constructed between 1728 and 1771 was the second-largest building in the country, only eclipsed in size by El Escorial in Madrid

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Tobacco 21 has been endorsed by most major medical organizations (here), and it has been adopted by six states: Hawaii (2015), California (2016), New Jersey (2017), Oregon (2017), Maine (2017) and Massachusetts (2018) (here)