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On Tuesday, Cronos confirmed that it was "engaged in discussions concerning a potential investment by Altria " but that "no agreement has been reached." And last week, The Wall Street Journal reported that Altria had held talks to take "a significant minority stake" in Juul, a three-year-old e-cigarette company based in San Francisco

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Tobacco use is the leading cause of preventable death, disease and disability in the United States, according to the Centers for Disease Control and Prevention

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Urgent referrals Adult patients with a clinically evident suspicious lesion, or symptom(s) suggestive of malignancy, ought to be given an immediate urgent referral to a specialist which should ensure an appointment within two weeks