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People who have decades of exposure to these carcinogens from vaping may be at risk for developing malignancies, especially bladder cancer. Future research is needed There were several limitations to the study, including that researchers did not know the levels of all of the cancer-causing substances in the urine of users from the studies

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With the tobacco industry's products, we allow them into the market and then have to prove they're dangerous, or very dangerous." * This article was updated on 2 May 2025 to make clear that the FDA issued additional authorisation for IQOS to be marketted in the US in 2020