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They include substances with medicinal properties that are legally available, such as benzodiazepines and opioid painkillers, as well as illegal drugs like heroin and methamphetamine that have no known therapeutic benefits and are used primarily for their psychotropic properties

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Public Health 106 , 315322 (1992)

However, the lack of consistently formulated and approved e-cigarette products and data on long-term safety may be an important deterrent for some people and practitioners

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