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Further studies are needed to elucidate the detailed mechanisms by which smoking induces endothelial dysfunction and to determine whether smoking cessation directly improves endothelial function

The smoking-induced damage to the endothelium thus curtails NO formation, leading to impotence.1 According to some experts, this endothelial-dependent impairment in relaxation and erection is reversible and depends on the frequency and the age of initiation of tobacco use.2 The relationship between smoking and impotence has been a subject of extensive research

26,27 In contrast to cigarette use, there is little evidence for reduced e-cigarette use in pregnant vs

L.AndrsE.PisteaC.CharlouxA.et al (2020)

Vaping vs Smoking: A Comparison of Nicotine Absorption The physiological process of absorbing vaporized nicotine differs from inhaling cigarette smoke in several key ways: Firstly, vapor penetrates deeper into the lungs, facilitating absorption into the bloodstream, unlike the heavier smoke particles that deposit nicotine quickly through the upper respiratory tract
