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A multicentric casecontrol study involving both Americans and Japanese was carried out and showed a striking results that the odds ratio (OR) of current US smokers relative to never smokers was 40.4, that was about 6 to 10 times higher than the OR ranging between 3.5 and 6.3 in current Japanese smokers [68]

It can also reduce inflammatory cytokines TNF- and IL-1 to simultaneously restore the level of neurotransmitters, including serotonin, dopamine, glutamate and acetylcholine, and reduce the markers of oxidative stress, thereby limiting the severity of this chronic mental disease

Lung cancers were among those with the highest numbers of somatic mutations (4.21 per megabase) and this was attributed to recurrent exogenous mutagen exposure

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They can be grouped into two different traditions