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In UCSF's CANDIDE study, Leila Mohammadi, MD, PhD, lead clinical investigator, found that chronic cannabis smokers had similar vascular functional defects to those of chronic tobacco smokers, including poorly functioning arteries, and blood serum that inhibited important properties of cultured endothelial cells (the inner lining of blood vessels)

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One study estimated it may even take 30 attempts over a smokers lifetime before they quit for good

These items have only recently been accepted into the mainstream of traditional smoke shops

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