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Endothelial dysfunction can be improved by appropriate pharmacotherapy [8,9,10,11], replacement therapy [12, 13], and lifestyle modifications including aerobic exercise [14, 15], body weight reduction [16], decrease in salt intake [17] and smoking cessation [18,19,20,21,22,23,24,25,26,27,28,29,30,31,32,33,34,35]

With a life expectancy of over 81 years, Germany was in the top quarter of the list.

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These findings reflect the significant impact of smoking on cardiovascular diseases and respiratory conditions

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