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Description

Briefly, the studies that were extracted represented several types of study design (for example, cohort and casecontrol studies), measured exposure in several different ways and varied in their choice of reference categories (where some compared current smokers with never smokers, whereas others compared current smokers with nonsmokers or former smokers)

The results of this study support health warnings that there is no safe level of exposure to tobacco smoke, said Maki Inoue-Choi, Ph.D., NCI, Division of Cancer Epidemiology and Genetics, and lead author of the study

To quantify the strength of the evidence, we calculated the ROS for each smokingoutcome association as the signed value of the log(BPRF) averaged between the 15th and 85th percentiles of observed exposure levels for each outcome