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Inasmuch, short-term e-cigarette use in healthy smokers resulted in marked impairment of endothelial function and an increase in arterial stiffness (reviewed in [20])

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At the other end of the scale was California and Vermont (both three percent) with the lowest rates with Connecticut second (3.2 percent)

In order to be marketed as an MRTP, a product must be scientifically substantiated to significantly reduce harm and/or exposure to harmful toxicants compared with continued smoking and benefit the health of the population as a whole